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SEROTONIN
Descriptors Found:
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DeCS
Descriptor
English
:
Serotonin
Descriptor
Spanish
:
Serotonina
Descriptor
Portuguese
:
Serotonina
Synonyms
English
:
3-(2-Aminoethyl)-1H-indol-5-ol
Enteramine
Hippophaine
Hydroxytryptamine
5 Hydroxytryptamine
5-HT
5-Hydroxytryptamine
Tree Number:
D02.092.211.215.801.852
D03.633.100.473.914.814
D23.469.050.650
Definition
English
:
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In
humans
it is found primarily in the
central nervous system
,
gastrointestinal tract
, and
blood platelets
.
Serotonin
mediates several important physiological functions including neurotransmission,
gastrointestinal motility
,
hemostasis
, and cardiovascular integrity. Multiple receptor families (RECEPTORS,
SEROTONIN
) explain the broad physiological actions and distribution of this biochemical mediator.
Indexing Annotation
English
:
/antag =
SEROTONIN ANTAGONISTS
but consider also
SEROTONIN UPTAKE INHIBITORS
Pharmacological Action:
Serotonin Receptor Agonists
Entry Combination - descr/qualif
English
:
Serotonin
/
agonists
use
Serotonin Receptor Agonists
Serotonin
/
antagonists & inhibitors
use
Serotonin Antagonists
See Related
English
:
Receptors, Serotonin
Serotonin Agents
Serotonin Syndrome
History Note
English
:
HYDROXYTRYPTAMINE was see SEROTONIN 1975-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AA
analogs & derivatives
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
24311
Unique Identifier:
D012701
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS