Search on: ZELAPAR 
Descriptors Found: 1
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Descriptor English:   Selegiline 
Descriptor Spanish:   Selegilina 
Descriptor Portuguese:   Selegilina 
Synonyms English:   E-250
Eldepryl
Emsam
Humex
Jumex
L-Deprenyl
Selegiline Hydrochloride
Selegiline Hydrochloride, (R)-Isomer
Selegiline Hydrochloride, (R,S)-Isomer
Selegiline Hydrochloride, (S)-Isomer
Selegiline, (R)-Isomer
Selegiline, (R,S)-Isomer
Selegiline, (S)-Isomer
Selegyline
Yumex
Zelapar
E 250
E250
Hydrochloride, Selegiline
Deprenalin
Deprenil
Deprenyl  
Tree Number:   D02.092.471.683.915
Definition English:   A selective, irreversible inhibitor of Type B monoamine oxidase. It is used in newly diagnosed patients with Parkinson's disease. It may slow progression of the clinical disease and delay the requirement for levodopa therapy. It also may be given with levodopa upon onset of disability. (From AMA Drug Evaluations Annual, 1994, p385) The compound without isomeric designation is Deprenyl. 
Pharmacological Action:   Antiparkinson Agents
Monoamine Oxidase Inhibitors
Neuroprotective Agents
 
History Note English:   91(84); was see under PHENETHYLAMINES 1984-90; was DEPRENYL see under PHENETHYLAMINES 1979-83 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   22667 
Unique Identifier:   D012642 

Occurrence in VHL: 		 

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