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NSC-125973
Descriptors Found:
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DeCS
Descriptor
English
:
Paclitaxel
Descriptor
Spanish
:
Paclitaxel
Descriptor
Portuguese
:
Paclitaxel
Synonyms
English
:
7-epi-Taxol
Anzatax
Bris Taxol
NSC-125973
Onxol
Paclitaxel, (4 alpha)-Isomer
Paxene
Praxel
Taxol
Taxol A
7 epi Taxol
NSC 125973
NSC125973
Taxol, Bris
Tree Number:
D02.455.426.392.368.242.888.777
D02.455.849.291.850.777
Definition
English
:
A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes
MICROTUBULES
in their polymerized form leading to
cell death.
Pharmacological Action:
Antineoplastic Agents, Phytogenic
Tubulin Modulators
History Note
English
:
95; was TAXOL 1993-94; was TAXOL A (NM) 1977-92
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
30485
Unique Identifier:
D017239
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS