Search on: METHIMAZOLE 
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Descriptor English:   Methimazole 
Descriptor Spanish:   Metimazol 
Descriptor Portuguese:   Metimazol 
Synonyms English:   1-Methyl-2-mercaptoimidazole
Favistan
Mercasolyl
Mercazol
Mercazole
Mercazolyl
Merkazolil
Methizol
Methylmercaptoimidazole
Metisol
Metizol
Strumazol
Tapazole
Thiamazol Henning
Thiamazol Hexal
Thimazol
Thyrozol
Tiamazol
Tirodril
1 Methyl 2 mercaptoimidazole
Henning, Thiamazol
Hexal, Thiamazol
Methymazol
Thiamazole  
Tree Number:   D02.886.489.600
D03.383.129.308.535
Definition English:   A thioureylene antithyroid agent that inhibits the formation of thyroid hormones by interfering with the incorporation of iodine into tyrosyl residues of thyroglobulin. This is done by interfering with the oxidation of iodide ion and iodotyrosyl groups through inhibition of the peroxidase enzyme. 
Pharmacological Action:   Antithyroid Agents
 
History Note English:   73(68); was see under THYROID ANTAGONISTS 1963-72 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   8890 
Unique Identifier:   D008713 

Occurrence in VHL:
 

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