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ICAM-3
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DeCS
Descriptor
English
:
Intercellular Adhesion Molecule-3
Descriptor
Spanish
:
Molécula 3 de Adhesión Intercelular
Descriptor
Portuguese
:
Molécula 3 de Adesão Intercelular
Synonyms
English
:
Antigens, CD50
CD50 Antigen
CDw50 Antigen
ICAM-3
ICAM3
Antigen, CD50
Antigen, CDw50
CD50 Antigens
Intercellular Adhesion Molecule 3
Tree Number:
D12.776.395.550.200.494
D12.776.543.550.200.494
D23.050.301.350.494
Definition
English
:
A membrane glycoprotein and
cell adhesion
molecule expressed by
LEUKOCYTES
that contains multiple Ig-like domains. It is a ligand for LFA-1 (integrin alphaLbeta2) and integrin alpha-D/beta-2. Its interaction with LFA-1 may play a role in the
PHAGOCYTOSIS
of
NEUTROPHILS
by
MACROPHAGES
following
APOPTOSIS.
See Related
English
:
Immunoglobulin Domains
History Note
English
:
2018
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
57125
Unique Identifier:
D000074001
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS