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DeCS
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Descriptor English:
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Anoctamins
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Descriptor Spanish:
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Anoctaminas
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Descriptor Portuguese:
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Anoctaminas
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Synonyms English:
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Anoctamin
TMEM16 Protein Family
TMEM16 Proteins
Protein Family, TMEM16
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Tree Number:
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D12.776.157.530.400.175.032
D12.776.543.550.450.175.032
D12.776.543.585.400.175.032
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Definition English:
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A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding. |
History Note English:
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2018
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Allowable Qualifiers English:
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Record Number:
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57079
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Unique Identifier:
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D000075368
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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