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MELANOPHORE STIMULATING HORMONE
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DeCS
Descriptor
English
:
Melanocyte-Stimulating Hormones
Descriptor
Spanish
:
Hormonas Estimuladoras de los Melanocitos
Descriptor
Portuguese
:
Hormônios Estimuladores de Melanócitos
Synonyms
English
:
MSH (Melanocyte-Stimulating Hormones)
Melanophore-Stimulating Hormone
Melanocyte Stimulating Hormones
Melanophore Stimulating Hormone
MSH
Melanotropin
Tree Number:
D06.472.699.327.935.531.750
D06.472.699.631.525.600.531.750
D12.644.400.400.935.531.750
D12.644.400.460
D12.644.548.365.935.531.750
D12.644.548.691.525.690.531.750
D12.776.631.650.405.935.531.750
D12.776.631.650.460
Definition
English
:
Peptides
with the ability to stimulate pigmented cells
MELANOCYTES
in
mammals
and
MELANOPHORES
in lower
vertebrates
. By stimulating the synthesis and distribution of MELANIN in these pigmented cells, they increase coloration of skin and other
tissue
. MSHs, derived from
pro-opiomelanocortin
(POMC), are produced by
MELANOTROPHS
in the INTERMEDIATE LOBE OF PITUITARY;
CORTICOTROPHS
in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic
neurons
in the
ARCUATE NUCLEUS OF HYPOTHALAMUS.
Pharmacological Action:
Hormones
History Note
English
:
2006(1963)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
23523
Unique Identifier:
D009074
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS