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DeCS
Descritor
Inglês
:
WW Domains
Descritor
Espanhol
:
Dominios WW
Descritor
Português
:
Domínios WW
Sinônimos
Inglês
:
WW Domain
Domain, WW
Domains, WW
Categoria:
G02.111.570.820.709.275.750.500.937
Definição
Inglês
:
An approximately 40 amino acid protein domain that occurs in a variety of unrelated
proteins
and may be repeated up to four times in some
proteins
. It is characterized by two
TRYPTOPHAN
residues (WW) about 20
amino acids
apart and folds into a stable triple-stranded BETA-SHEET. It binds
PROLINE-RICH PROTEIN DOMAINS
and
PHOSPHOSERINE
or PHOSPHOTHREONINE-containing
protein domains
that occur in many signal transducing and
cytoskeletal proteins
, such as
DYSTROPHIN.
Nota Histórica
Inglês
:
2018
Qualificadores Permitidos
Inglês
:
DE
drug effects
GE
genetics
IM
immunology
PH
physiology
RE
radiation effects
Número do Registro:
57257
Identificador Único:
D000074585
Ocorrência na BVS
:
Similar:
DeCS
CID-10
LILACS