Search on: ALPHA-TRICHOSANTHIN 
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Descriptor English:   Trichosanthin 
Descriptor Spanish:   Tricosantina 
Descriptor Portuguese:   Tricosantina 
Synonyms English:   GLQ-223
GLQ223
T'ien-hua-fen
Tian-hua-fen
GLQ 223
alpha Trichosanthin
alpha-Trichosanthin
Compound Q  
Tree Number:   D12.776.765.710.500.500
Definition English:   Plant-derived ribosome-inactivating protein (RIP) purified from the Chinese medicinal herb tian-hua-fen which is obtained from the root tubers of Trichosanthes kirilowii. It has been used as an abortifacient and in the treatment of trophoblastic tumors. GLQ223 (Compound Q), a highly purified form of trichosanthin, has been proposed as antiviral treatment for AIDS. 
Indexing Annotation English:   /drug eff /ultrastruct permitted
Pharmacological Action:   Abortifacient Agents, Nonsteroidal
Anti-HIV Agents
Antineoplastic Agents, Phytogenic
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   24902 
Unique Identifier:   D015978 

Occurrence in VHL:
 

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