Search on: TRYPTOPHANASE 
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Descriptor English:   Tryptophanase 
Descriptor Spanish:   Triptofanasa 
Descriptor Portuguese:   Triptofanase 
Synonyms English:   Indole-Lyase, Tryptophan
Tryptophan Indole Lyase
Tryptophan Indole-Lyase  
Tree Number:   D08.811.520.224.800
Definition English:   An enzyme that catalyzes the conversion of L-tryptophan and water to indole, pyruvate, and ammonia. It is a pyridoxal-phosphate protein, requiring K+. It also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine, and other 3-substituted amino acids. (From Enzyme Nomenclature, 1992) EC 4.1.99.1. 
History Note English:   91(72); was see under LYASES 1972-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   14770 
Unique Identifier:   D014368 

Occurrence in VHL:
 

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