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JAGGED-1
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DeCS
Descriptor
English
:
Jagged-1 Protein
Descriptor
Spanish
:
Proteína Jagged-1
Descriptor
Portuguese
:
Proteína Jagged-1
Synonyms
English
:
Alagille Syndrome Protein
CD339 Antigen
Jagged-1
Jagged1 Protein
Serrate-1 Protein
Serrate1 Protein
Antigen, CD339
Jagged 1
Jagged 1 Protein
Serrate 1 Protein
Tree Number:
D12.644.276.930.500
D12.776.157.125.797.500
D12.776.543.800.500
D23.529.930.500
Definition
English
:
A serrate-jagged protein that functions as a ligand for NOTCH RECEPTORS. It may regulate
CELL DIFFERENTIATION
in
HEMATOPOIESIS
and PHYSIOLOGIC ANGIOGENESIS.
Mutations
in the Jagged-1 gene are associated with
ALAGILLE SYNDROME
1.
History Note
English
:
2017 (1991)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56530
Unique Identifier:
D000072100
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS