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IMATINIB
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DeCS
Descriptor
English
:
Imatinib Mesylate
Descriptor
Spanish
:
Mesilato de Imatinib
Descriptor
Portuguese
:
Mesilato de Imatinib
Synonyms
English
:
Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide
CGP 57148
CGP-57148
CGP57148B
Gleevec
Glivec
Imatinib
Imatinib Methanesulfonate
ST 1571
ST1571
STI 571
STI-571
STI571
CGP57148
Mesylate, Imatinib
Methanesulfonate, Imatinib
Tree Number:
D02.065.277.456
D02.241.223.100.100.435
D02.455.426.559.389.127.085.465
D03.383.606.405
D03.383.742.349
Definition
English
:
A
tyrosine
kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by
chromosome
rearrangements in CHRONIC MYELOID
LEUKEMIA
and ACUTE LYMPHOBLASTIC
LEUKEMIA
, as well as PDG-derived
tyrosine
kinases that are overexpressed in
gastrointestinal stromal tumors.
History Note
English
:
2016 (1996)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
55873
Unique Identifier:
D000068877
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS