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Descriptor English:   Erythromycin Estolate 
Descriptor Spanish:   Estolato de Eritromicina 
Descriptor Portuguese:   Estolato de Eritromicina 
Synonyms English:   Eromycin
Erythromycin Propionate Monododecyl Sulfate
Ilosone
Lauromicina
Estolate, Erythromycin
Erythromycin Propionate Dodecyl Sulfate
Erythromycin Propionate Lauryl Sulfate  
Tree Number:   D02.540.576.500.992.250
Definition English:   A macrolide antibiotic, produced by Streptomyces erythreus. It is the lauryl sulfate salt of the propionic ester of erythromycin. This erythromycin salt acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. 
Pharmacological Action:   Anti-Bacterial Agents
Enzyme Inhibitors
Gastrointestinal Agents
Protein Synthesis Inhibitors
 
History Note English:   91(75); was see under ERYTHROMYCIN 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   28028 
Unique Identifier:   D004918 

Occurrence in VHL:
 

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