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DIGOXIN
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DeCS
Descriptor
English
:
Digoxin
Descriptor
Spanish
:
Digoxina
Descriptor
Portuguese
:
Digoxina
Synonyms
English
:
Digacin
Digitek
Digoregen
Digoxina Boehringer
Digoxine Nativelle
Dilanacin
Hemigoxine Nativelle
Lanacordin
Lanicor
Lanoxicaps
Lanoxin
Lanoxin-PG
Lenoxin
Mapluxin
Boehringer, Digoxina
Lanoxin PG
Nativelle, Digoxine
Nativelle, Hemigoxine
Tree Number:
D04.210.500.155.580.130.500.436
D04.210.500.155.580.130.688
D09.408.180.261.436
Definition
English
:
A cardiotonic glycoside obtained mainly from
Digitalis
lanata; it consists of three
sugars
and the aglycone
DIGOXIGENIN
.
Digoxin
has positive inotropic and negative chronotropic activity. It is used to
control
ventricular rate in
ATRIAL FIBRILLATION
and in the management of congestive
heart failure
with
atrial fibrillation
. Its use in congestive
heart failure
and sinus rhythm is less certain. The
margin
between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
Indexing Annotation
English
:
do not confuse with
DIGITOXIN
Pharmacological Action:
Anti-Arrhythmia Agents
Cardiotonic Agents
Enzyme Inhibitors
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis
AI
antagonists & inhibitors
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
EC
economics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
4116
Unique Identifier:
D004077
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS