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APOPAIN
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DeCS
Descriptor
English
:
Caspase 3
Descriptor
Spanish
:
Caspasa 3
Descriptor
Portuguese
:
Caspase 3
Synonyms
English
:
Apopain
Caspase-3
Pro-Caspase-3
Procaspase-3
Pro Caspase 3
Procaspase 3
CASP3
Tree Number:
D08.811.277.656.262.500.126.350.300
D08.811.277.656.300.200.126.350.300
D12.644.360.075.405.350.300
D12.776.476.075.405.350.300
Definition
English
:
A short pro-domain caspase that plays an effector role in
APOPTOSIS
. It is activated by
INITIATOR CASPASES
such as
CASPASE 9
. Isoforms of this protein exist due to multiple
alternative splicing
of its MESSENGER RNA.
Entry Combination - descr/qualif
English
:
Caspase 3
/
antagonists & inhibitors
use
Caspase Inhibitors
History Note
English
:
2007(1995)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
52221
Unique Identifier:
D053148
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS