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ACAMP-81
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DeCS
Descriptor
English
:
Myristoylated Alanine-Rich C Kinase Substrate
Descriptor
Spanish
:
Sustrato de la Proteína Quinasa C Rico en Alanina Miristoilada
Descriptor
Portuguese
:
Substrato Quinase C Rico em Alanina Miristoilada
Synonyms
English
:
ACAMP-81
MARCKS Protein
Myristoylated Alanine Rich C Kinase Substrate
Tree Number:
D05.750.078.730.556
D12.644.360.537
D12.776.157.142.375
D12.776.157.687.496
D12.776.220.525.556
D12.776.476.539
D12.776.543.637
D12.776.660.720.496
Definition
English
:
A membrane and
ACTIN CYTOSKELETON
associated, N-terminal myristoylated protein that binds
CALMODULIN
and is a prominent substrate for
PROTEIN KINASE C
. Both
phosphorylation
and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity;
phosphorylation
also causes MARCKS to relocate from the membrane to
cytoplasm.
History Note
English
:
2018 (1989)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56988
Unique Identifier:
D000076250
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS