Pesquisa sobre: MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES 
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Descritor Inglês:   Mannose-Binding Protein-Associated Serine Proteases 
Descritor Espanhol:   Serina Proteasas Asociadas a la Proteína de Unión a la Manosa 
Descritor Português:   Serina Proteases Associadas a Proteína de Ligação a Manose 
Sinônimos Inglês:   MASP Proteases
MASP-Related Protein
MASPs
MBL-Associated Serine Proteases
MBP-Associated Serine Protease
MBP-Associated Serine Protease-Related Protein
Mannan-Binding Lectin Serine Proteases
Mannose-Binding Protein-Associated Serine Protease
MASP Related Protein
MBL Associated Serine Proteases
MBP Associated Serine Protease
MBP Associated Serine Protease Related Protein
Mannan Binding Lectin Serine Proteases
Mannose Binding Protein Associated Serine Protease
Proteases, MASP
Protein, MASP-Related
Serine Protease, MBP-Associated
Serine Proteases, MBL-Associated  
Categoria:   D08.811.277.656.300.760.501
D08.811.277.656.959.350.501
D12.776.124.486.274.045.387.875
Definição Inglês:   Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE. 
Nota de Indexação Inglês:   see SCR for organism-specific terms
Ação Farmacológica:   Immunologic Factors
 
Nota Histórica Inglês:   2006 (1994) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número do Registro:   50582 
Identificador Único:   D050606 

Ocorrência na BVS:
 

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