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TRP53 PROTEIN
Descriptors Found:
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DeCS
Descriptor
English
:
Tumor Suppressor Protein p53
Descriptor
Spanish
:
Proteína p53 Supresora de Tumor
Descriptor
Portuguese
:
Proteína Supressora de Tumor p53
Synonyms
English
:
Cellular Tumor Antigen p53
Oncoprotein p53
TP53 Protein
TRP53 Protein
p53 Antigen
pp53 Phosphoprotein
Phosphoprotein, pp53
p53 Tumor Suppressor Protein
Tree Number:
D12.776.157.687.650
D12.776.260.820
D12.776.624.776.775
D12.776.660.720.650
D12.776.744.845
Definition
English
:
Nuclear phosphoprotein encoded by the p53 gene (GENES, P53) whose normal function is to
control
CELL PROLIFERATION
and
APOPTOSIS
. A mutant or absent p53 protein has been found in
LEUKEMIA
;
OSTEOSARCOMA
; LUNG CANCER; and COLORECTAL CANCER.
History Note
English
:
2005(1991);
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29089
Unique Identifier:
D016159
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS